Search In this Thesis
   Search In this Thesis  
العنوان
Development of validated modern analytical methods for the determination of certain pharmaceutical mixtures /
الناشر
Salah Aldeen Mohammed Qassim Alsanousi ,
المؤلف
Salah Aldeen Mohammed Qassim Alsanousi
هيئة الاعداد
باحث / Salah Aldeen Mohammed Qassim Alsanousi
مشرف / Mohammad Abdul-Azim Mohammad
مشرف / Ehab Farouk Elkady
مشرف / Marwa Ahmed Fouad
تاريخ النشر
2019
عدد الصفحات
175 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
30/11/2019
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Pharmaceutical Chemistry
الفهرس
Only 14 pages are availabe for public view

from 214

from 214

Abstract

Different methods for determination of certain drugs in laboratory mixtures and in pharmaceutical dosage forms have been applied in this thesis. These drugs are hydrochlorothiazide, bisoprolol fumarate, candesartan cilexetil, atenolol, amlodipine besylate, aspirin, paracetamol and omeprazole. chromatographic part includes the use of HPLC for simultaneous determination of hydrochlorothiazide, bisoprolol fumarate and candesartan cilexetil in laboratory mixture and in two different dosage forms, and, simultaneous determination of atenolol, aspirin and amlodipine besylate in presence of aspirin degradation product in laboratory prepared mixture and dosage form and simultaneous determination of aspirin, omeprazole and paracetamol in presence of aspirin degradation product in laboratory prepared mixture and in two different dosage form.Spectroscopic part includes the use of PCR, PLS and ANN chemometric techniques for simultaneous determination of atenolol, amlodipine and aspirin and simultaneous determination of hydrochlorothiazide and bisoprolol fumarate in presence of hydrochlorothiazide degradation product