الفهرس 
INTRODUCTION AND RATIONALEOnly 14 pages are availabe for public view
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Abstract
Androgenetic alopecia (AGA) is the most common pattern of
loss of scalp hair in both men and women. The hair loss appears to
be caused by a combination of genetic predisposition and hormonal
triggers. These lead to shortening of the anagen phase of the hair
cycle and miniaturization of the hair follicle, eventually resulting in
transformation of the hair follicle from one capable of producing
long terminal pigmented hairs to one that produces only short fine
vellus hair. Such transformations occur in a programmed pattern
across particular regions of the scalp, resulting in a characteristic
balding pattern.
Androgenetic alopecia is defined as a chronic, diffuse,
progressive hair loss. Patients have hair loss in a ratio of 2 : 1, that
is, for every 2 new hair threads; one is lost.
The hair loss usually begins between the ages of 12 and 40
years and is frequently insufficient to be noticed. However, visible
hair loss occurs in approximately one half of all persons by the age
of 50 years.
Female Pattern Hair Loss (FPHL) has emerged as the
preferred term for androgenic alopecia in females owing to the
uncertain relationship between androgens and this entity. It is
characterized by a reduction in hair density over the crown and
frontal scalp with retention of the frontal hairline.
Summary and conclusion 69
Usually, women do not suffer classic male pattern baldness.
In women, the hair becomes thinner all over the head, and the
hairline does not recede. This is called ”Female pattern baldness”
and may occur in males. This variety of androgenic alopecia in
women rarely leads to total baldness.
Hair loss in women is associated with significant
psychological morbidity suggested that women place a greater
emphasis than men on physical appearances and outward
attractiveness. Hair is an essential part of a woman’s sexuality and
gender identity, and any hair loss generates feelings of low selfesteem
and anxiety from a perception of diminished attractiveness.
The clinical picture of typical Female Pattern Hair Loss
(FPHL) begins with a specific ”diffuse loss of hair from the parietal
or frontovertical areas with an intact frontal hairline”; this process
”rarefaction”. In Ludwig’s classification of hair loss in women,
progressive type of FAGA, 3 patterns were described: grade I or
minimal, grade II or moderate, and grade III or severe.
Studies have determined relatively Increased risk of
coronary heart disease (CHD) in Androgentic alopecia (AGA). They
revealed a meaningful association between AGA and
hyperlipidemia. Androgentic alopecia associated with significantly
increase total cholesterol and LDL-cholesterol. Furthermore, studies
have shown that the pattern of lipid profile of patients with AGA
predisposes them to CAD.
Summary and conclusion 71
There is a correlation between androgenic alopecia (AGA)
and life-threatening diseases, such as coronary artery disease (CAD).
The frequency of CAD has been shown to increase in AGA. The
relationship of CAD with AGA has been demonstrated, but few
studies have focused on the mechanism of this association.
Few studies have focused on this association in females with
AGA and dyslipidemia that be considered as a risk factor for many
threatening life diseases. Female Androgenetic Alopecia, like male
pattern baldness, was associated with CAD in women younger than
55 years.
Dermatologists should investigate the lipid parameters,
especially total cholesterol and LDL-cholesterol in female patients
AGA as evaluative measure.
The aim of this study was to detect correlation between the