الفهرس 
PharmacologyOnly 14 pages are availabe for public view
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Abstract
Abstract
Anesthetic techniques have always been tailored to obtain the most appropriate conditions, and to reduce the perioperative complications in many special surgical procedures. Transversus abdominis plane (TAP) block is a fascial plane block that can be used to decrease pain after abdominal surgeries. Adjuvants or additives are often used with local anesthetics for its synergistic effect by prolonging the duration of sensory-motor block and limiting the cumulative dose requirement of local anesthetics.
In this comparative, randomized, clinical study, a group sample size of 25 cases per group, totaling 50 cases in the study. This study was designed to compare two different concentration of Bupivacaine 0.25% versus 0.125% added to 50 u Dexmedetomidine as adjuvant in TAP block on quality of analgesia for postoperative pain for parturient undergoing elective Cs.
In the ward the VAS score, vital data (Mean blood pressure, heart rate) 6, 12,18,24, timing of first rescue dose of nalbuphine used postoperatively/patient (rescue analgesia) and side effects: Hypotension, Bradycardia, nausea will be recorded. If VAS ≥ 3 postoperatively, increment of nalbuphine 4 mg will be given. Any side effects will be recorded as hypotension (systolic arterial pressure <90 mmHg), arrhythmia, bradycardia (HR <50 beat/min), nausea or vomiting, or any other complications.
We found that Bupivacaine 0.125% with dexmedetomidine is recommended regarding their analgesic properties, and moreover, Bupivacaine 0.25% with dexmedetomidine was proved to prolong the analgesic effect of TAP block in elective CS even with the higher concentrations of local anesthetics is our concern