الفهرس 
Spontaneous Bacterial PeritonitisOnly 14 pages are availabe for public view
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Abstract
Background; Spontaneous bacterial peritonitis (SBP) is a serious, recurrent, and life-threatening condition developing in cirrhotic patients with a high mortality rate. Its diagnosis is based on ascitic fluid polymorphonuclear leukocytes (PMNs) to be more than 250/μL. Endocan is a proteoglycan (PG) secreted by vascular endothelium, its serum level is elevated with an inflammatory or a malignant process, Aim and objectives; to evaluate the potential role of ascitic fluid levels of endocan as an appropriate marker for prediction and early diagnosis of spontaneous bacterial peritonitis in patients with liver cirrhosis, Subjects and methods: This was Prospective cohort study, was conducted in hepatology Unit of Ain Shams University Hospital over 100 patients with liver cirrhosis classified into two groups: (Non-SBP): included 50 patients of decompensated cirrhosis with sterile (non SBP) ascites, (SBP): included 50 Adult patients with liver cirrhosis and SBP, during a Period 6 months. All patients were subjected to: Full history taking, Clinical examination, Routine investigations, Radiology investigations, Determination of ascitic endocan levels by ELISA, Result; There, Conclusion; In conclusion, this study demonstrates that ascitic endocan level is an independent risk factor for SBP and has a high diagnostic value for detecting SBP in patients with decompensated cirrhosis,