الفهرس 
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Abstract
The objectives of this study was to compare the effect of Bacillus strains probiotic mixture (BS) or Yucca shidigera liquid extract (YSE) alone or their combination in water bioremediation and in reliving toxicity of an acute ammonia challenge in Nile tilapia through The assessment of fish immune response, inflammatory pathway, oxidative stress response with respect to the histopathological changes, gene expression, enzymes levels and phagocytosis.
The use of Bacillus strains probiotic mixture (BS), Yucca shidigera liquid extract (YSE) in relieving ammonia toxicity in fish significantly restored water pH, and a maintained ammonia level compared to the control level. They significantly improved antioxidant enzymes activities, phagocytic activity, tissue histopathology, and modulated the expression of some inflammatory, antioxidant and immune related genes. However, the most pronounced modulation was observed when BS-YSE mix was used. We recommend the used of this mixture for water ammonia bioremediation and relieving ammonia toxicity in fish.