الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Multiple myeloma (MM) is a malignant lymphoid hematological cancer of the B cells that is defined by the growth of a plasma cell clone that produces monoclonal immunoglobulin in the bone. It makes for around 10% of all hematologic malignancies. Its medullary osseous tropism, which is the cause of significant morbid-mortality, distinguishes it. About 60% of patients have a pathological fracture, and up to 90% of patients experience osteolytic lesions during the disease. The staging, treatment evaluation, and prognosis of these lesions depend heavily on their discovery. WB-MRI is increasingly relevant for the assessment of patients with MM due to its complete body coverage and excellent sensitivity for bone marrow involvement before or without bone destruction. Whole-body diffusion magnetic resonance imaging with background body signal suppression (DWIBS) was first described by Takahara et al. in 2004 and is used for oncological imaging. WB-MRI with DWIBS could detect myeloma bony lesions, as well as soft tissue component and vertebral compression. The main goal of this study is to assess role of whole-body diffusion magnetic resonance imaging with background body signal suppression (DWIBS) in the evaluation of MM patients.