الفهرس 
Polycystic Ovary Syndrome
Visceral Obesity (VO) in PCOS WomenOnly 14 pages are availabe for public view
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Abstract
Polycystic ovary syndrome (PCOS) is a common disorder in women of reproductive age, with a prevalence 5–16% under different diagnostic criteria and across several ethnic groups, with exact pathogenesis still unclear.(1) Polycystic ovary syndrome (PCOS) is a multifactorial, heterogeneous, endocrine-metabolic disorder that commonly affects women at their reproductive age. PCOS is a complex syndrome characterized by chronic oligo-or anovulation, menstrual irregularities, hyperandrogenism, infertility, and polycystic ovarian morphologic features.(2) The diagnosis of PCOS based on the Rotterdam criteria, Women with the two of the following criteria were considered as having PCOS: oligoovulation and anovulation, biochemical signs of hyperandrogenism, and polycystic ovaries on ultrasound examination (defined as the presence of 12 follicles measuring 2-9 mm in diameter and/or an ovarian volume >10 cm3).(3) Excess luteinizing hormone (LH) and low follicle stimulating-hormone (FSH) are also common, and approximately 60%–80% of all PCOS cases are more vulnerable to develop insulin resistance (IR) and compensatory hyperinsulinemia, which exacerbates ovarian androgen production and ovulation dysfunction in PCOS patients. (4) The presence of hyperinsulinemia and insulin resistance is associated with an increased risk for impaired glucose tolerance, cardiovascular disease and type 2 diabetes mellitus. Many studies indicate that a defect in insulin action may be the primary cause of PCOS. (5,6).