الفهرس 
Gastric Emptying and Gastric Residual VolumeOnly 14 pages are availabe for public view
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Abstract
Background: Oral Dopmeridone is a prokinetic drug that enhance gastric emtptying, which has a positive effect in decreasing the gastric residual volume, subsequently decreasing the risk of pulmonary aspiration
Aim of the work: This study to aimed to assess the effect of oral Domperidone preoperatively on gastric residual volume by ultrasound for patients undergoing elective surgeries under general anesthesia as a primary outcome and postoperative nausea and vomiting as a secondary outcome.
Patients and Methods: We applied our study on 40 patients were divided into two equal groups: group A (study group): The patients received 400 ml of apple juice as a clear fluid, two hours preoperatively, and oral Domperidone tab (Motilium 10mg/tab, Janssen comp.) & group B (control group): The patients received 400 ml of apple juice as a clear fluid two hours preoperatively with a placebo (Folic acid 500 mcg, dietary supplement), with the same inclusion and exclusion criteria.
Results: There was statistically significant decrease mean in group A compared to group B according to Ultrasound Measurements in the right lateral position after 2 hrs has been demonstrated about D1 right lateral position; D2 right lateral position; CSA right lateral position and calculated gastric volume right lateral position (ml). In addition to a statistically significant decrease mean in after 2hrs. compared to after 1hr. according to Ultrasound Measurements in the right lateral position about D1 right lateral position; D2 right lateral position; CSA right lateral position and Calculated gastric volume right lateral position (mL) in group A. There is also a statistically significant decrease mean in after 2hrs. compared to after 1hr. according to Ultrasound Measurements in the right lateral position about D1 semi-sitting; D2 right lateral; CSA right lateral position and Calculated gastric volume right lateral position (mL) in group B. At last, there has been a statistically significant higher change (after 2hrs.-1hr.) in group A compared to group B according to Ultrasound Measurements in the right lateral position about D1 right lateral position; D2 right lateral position; CSA right lateral position and Calculated gastric volume right lateral position (mL), with p-value (p<0.05 significant).
Conclusion: Preoperative oral Domperidone intake was able to decrease the GRV measured by ultrasound, more than the decrease of GRV by applying placebo.