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Abstract Neonatal asphyxia causes hypoxia and leads to multiple organ damage, of which heart damage is the most common. The occurrence of myocardial damage in neoantal asphyxia was 28-65% or even up to 73%. However, the diagnosis of hypoxic-ischemic myocardial damage has been difficult because of the lack of sensitive laboratory tests for early diagnosis and the absence of standard diagnostic criteria. In the study of myocardial infarction, an increase in the BNP/NT-proBNP level appears to be correlated with the timing and extent of myocardial infarction. Therefore, the BNP/NT-proBNP level is useful for the detection of chronic ventricular dysfunction in adults and congestive heart failure in patietns with breathing difficulty; the BNP/NT-proBNP level allows for the diagnosis of subclinical asymptomatic patients with left ventricular abnormalities. |