الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 134 |  |  |
| | | from | 134 | | |
Abstract
Purpose: To evaluate level of omentin-1 in hirsute female in comparison with normal non hirsute women. Also to find a possible relation between omentin-1 level, severity of hirsutism and PCO. Materials and methods This research included 42 diagnosed with hirsutism (21 idiopathic, 21 PCO associated hirsutism) and 42 healthy matched control . They were chosen randomly from the Laser Unit in Dermatology Department of Mansoura University Hospital’s. Typical clinical results were used to diagnose the patients. The following data were calculated for all patients and the control group: age duration of the disease, onset of puberty, menstrual cycle duration and regularity, previous gynecological treatments, family history of PCOS, body hair distribution. Severity was categorized according to modified Ferriman Gallwey. Results Higher omentin-1 level was significantly associated with idiopathic hirsutism when compared to hirsutism with PCO subgroups, Omentin-1 level showed significant negative correlations with degree of hirsutism, TT, FBG, insulin levels and HOMA-IR, Positive FH and irregular menses were significantly associated with hirsutism with PCO when compared to idiopathic hirsutism. Conclusions : omentin-1 could have a protective effect against higher degree of hirsutism, acne, obesity, insulin resistance, hormonal abnormalities in hirsute females. Omentin-1 level could be used as reliable indicator in discrimination between idiopathic hirsutism and those with PCO. Keywords: omentin-1,PCOS,hirsutism.