الفهرس 
LITERATURE REVIEWOnly 14 pages are availabe for public view
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Abstract
Zygomatico-maxillary complex (ZMC) fracture is one of the most common maxillofacial fractures. Nowadays, the standard treatment of zygomatic bone fracture is fixation with micro-plates or mini-plates and screws. However, it is very difficult to place plates and screws into thin bones or small bone fragments especially in the facial bones and bones adjacent to important structures.N-2-Butyl cyanoacrylate (Histoacryl) is a bone adhesive material used in bone cementation in craniofacial fractures.
Aim: To compare the clinical and histological healing performance of histoacryl versus conventional microplates in ZMC fracture in rabbit.
Material and methods: Twelve New Zealand white rabbits weighing 3.5–4.5 kg were chosen. Unilateral ZMC fracture was done. Animals were divided randomly into group A (control group); six ZMC fractures were fixed by microplates, and group B (study group); six ZMC fractures were fixed by histoacryl. The treatment sites were evaluated Clinically, Histologically, and Histomorphometrical after one, four and 6 weeks.
Results: Clinical results showed no infection or mobility in any animals of both groups. Histological results, by the end of the first week, the histoacryl group showed less granulation tissue and mild inflammation compared to the control with woven bone formation. Microplate group showed more granulation tissue with finely woven bone spicules at the side of the fracture area. In the fourth week, the control group showed mature bone formation at the fracture site’s border while the center was still full of granulation tissue. The histoacryl group exhibited complete closure of the fracture site with mature lamellar bone. In the sixth week both grups showed complete bone formation and closure of fracture area. These results were confirmed by histomorphometric analysis, there was significantly increase in the percentage of bone surface area in the histoacryl the mean was( 49.55, 65.04 and 37.06) in 1,4 and 6 weeks respectivly while in control group was(46.40, 56.40 and 69.47).
Conclusion: The application of histoacryl to bone fractures shows easy and adequate rigid fixation to allow bone healing and maintain the original contour of the zygomatic bone comparable to the conventional microplates.