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العنوان
Accuracy of dermoscopic scoring in vitiligo in relation to clinical scoring and serological cxcl10 serum level/
المؤلف
Elsayed, Ahmed Hassan Ibrahim.
هيئة الاعداد
مشرف / فيروز خليل بدران
مشرف / خالد فوزي الملا
مشرف / نجلاء فتحى عجميه
مشرف / رشا عبد المولي غزالة
الموضوع
Dermatology. Venereology. Andrology.
تاريخ النشر
2023.
عدد الصفحات
89 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الأدوية (الطبية)
تاريخ الإجازة
17/1/2023
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Department of Dermatology, Venereology and Andrology
الفهرس
Only 14 pages are availabe for public view

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Abstract

Vitiligo is a common pigmentary disorder, of great sociomedical importance, affecting nearly 1–2% of the population. It is defined clinically as sharply demarcated, acquired, idiopathic, progressive, depigmentation of skin and hair, and is characterized by total absence of melanocytes microscopically.
Vitiligo can be extremely disfiguring, leading to significant patient morbidity. Low self-esteem, poor body image and poor quality of life have been found in patients with vitiligo, especially in individuals of darker skin types.
It remains unclear what causes damage to melanocytes and their subsequent disappearance in affected skin. There are several pathophysiologic theories; the most prominent are genetic, neural, autoimmune, oxidative stress theory, apoptotic theory and convergence theory.
Vitiligo has been classified based on clinical grounds into two major forms, segmental vitiligo (SV) and non-segmental vitiligo (NSV), the latter including several variants (generalized, acrofacial and universal).
Several scoring systems are currently available for assessing the clinical severity of vitiligo. However, there is still no standardized method. The VASI is one of the most frequently cited measurement methods for assessing vitiligo. These methods range from: subjective methods, semi-subjective methods and objective methods.