الفهرس 
Title: Clinical and radiological predictors of morbidity and mortality in hospitalized infant and children with acute lower respiratory tract infection
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Abstract
Acute lower respiratory tract infection (ALRI) remains a leading cause of hospitalization among infants and children globally and it is one of the leading causes of morbidity and mortality in under fives. The aim was to study the associations between the clinical factors and admission chest radiographic findings with the clinical outcomes among children and infant hospitalized with ALRI. Patients and Methods:Our study included 120 children hospitalized with ALRI in Cairo University{u2019}s Children hospitals, aged 2{u2013}59 months from November 2016 to February 2017. They were closely followed up for the duration hospital stay, ICU admission, need for mechanical ventilation(MV) or continuous positive airway pressure (CPAP) and mortality. Data on the factors influencing the outcome were collected. Results:Of 120 children enrolled in the study, 26 patients (21.7%) required ICU admission, 6 patients (5%) needed CPAP, and 8 patients (6.7%) required MV. The mean duration of hospital admission was 11.18 days ± 4.69. from out of 120 patients, one patient (0.8%) died during the study period.Patient{u2019}s weight (P 0.004), capillary filling time (P 0.002), Glasgow coma scale(P<0.001) and initial O2saturation (P<0.001) and arterial PO2(P 0.001)were associated with the need to ICU admission. Respiratory rate (P 0.004), capillary filling time (P 0.046), Glasgow coma scale(P<0.001), and Initial oxygen saturation (P 0.001), pH, pO2 and pCO2 were associated with the need to CPAP or MV. History of exclusive breast feeding for 6 months(P 0.041), temperature (P<0.001) and respiratory rate(P 0.007), patient{u2019}s height(P 0.009), presence of crepitation (P<0.001), hemoglobin and TLC, serum CRP, positive blood culture and abnormal radiological findings (P< 0.001) were identified as determinants for prolonged hospital stay