الفهرس 
Intravenous dexmedetomidine versus midazolam as sedatives with peribulbar blocks for cataract surgery monitored by Bispectral- Index (Randomized Controlled Trial)
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Abstract
Although local anesthesia is preferred in ophthalmic surgery compared to general anesthesia, there are still several adverse effects such as pain, fear and anxiety. Various sedative drugs such as propofol, midazolam, and opioids have been used for cataract surgery. However, these drugs have several adverse effects including respiratory depression, cardiovascular depression, over-sedation, disorientation and may interfere with patient cooperation during surgery. Dexmedetomidine is a strong selective, specific Ü2-adrenergic agonist that has dose-related sedative and analgesic properties without causing respiratory depression. Its mechanism of action is similar to natural sleep and arousability is maintained at deep levels of sedation, with good correlation between the level of sedation and the bispectral index (BIS)