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العنوان
Effect of intensity modulated radiotherapy on outcomes of head and neck cancer :
الناشر
Asmaa Abdelmonem Abdelmajeed Mostafa ,
المؤلف
Asmaa Abdelmonem Abdelmajeed Mostafa
هيئة الاعداد
باحث / Asmaa Abdelmonem Abdelmajeed Mostafa
مشرف / Tamer Ibrahim Enahas
مشرف / Hanan Selim Musalam
مشرف / Ashraf Mounir Moris
تاريخ النشر
2017
عدد الصفحات
141 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأورام
تاريخ الإجازة
12/5/2018
مكان الإجازة
جامعة القاهرة - كلية الطب - oncology (Clinical)
الفهرس
Only 14 pages are availabe for public view

from 154

from 154

Abstract

Background: Radiotherapy is the most important therapeutic treatment for head and neck cancer (HNC) patients. Radiation techniques has emerged rapidly from 2D-RT to 3D-CRT then IMRT. Numerous studies have shown that IMRT can deliver an adequate dose to gross tumor while sparing the surrounding normal tissues causing better local control rates. Therefore, the aim of our retrospective study was to assess whether IMRT can improve clinical outcomes when compared to 2D-RT or 3D-CRT in patients with head and neck cancer. Aim of the work: The aim of this retrospective study was to compare the survival and toxicity in head and neck cancer patients treated with either IMRT or non IMRT technique in the Center of Clinical Oncology and Nuclear Medicine (NEMROCK) Material &Methods: The medical records of patients with squamous cell carcinoma of head and neck cancers were treated at our center in a period between 2005 and 2011 were reviewed. Patients included in this study were 18 years or above, both genders, undergone radiotherapy either (adjuvant) or definitive radiotherapy with either (2D, 3DCRT or IMR with or without CCRT. The survival rates were assessed by Kaplan-Meier curves and the influence of covariates on OS and PFS were evaluated with the univariate log-rank test. The Cox{u2019}s proportional prognostic hazard was used to determine independent factors