![]() | Only 14 pages are availabe for public view |
Abstract Despite the availability of newer antifungal drugs, outcomes for patients with invasive fungal infections (IFIs) continue to be poor, in large part due to delayed diagnosis and initiation of appropriate antifungal therapy. Standard histopathologic diagnostic techniques are often untenable in at-risk patients, and culture-based diagnostics typically are too insensitive or nonspecific, or provide results after too long time causing a delay for optimal IFI management (Zeichner, 2011). Candida is the main etiological agent of opportunistic mycoses worldwide and is associated with high mortality rates (Taira et al., 2014) It can cause severe mucosal and life threatening invasive infections, invasive candidiasis (IC) and disseminated candidiasis including blood stream infections |