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العنوان
Expression of activated molecules on CD5+B cells in autoimmune hemolytic anemia /
الناشر
Heba Ahmed Ramadan Basuny ,
المؤلف
Heba Ahmed Ramadan Basuny
هيئة الاعداد
باحث / Heba Ahmed Ramadan Basuny
مشرف / Zakarya Ismail
مشرف / Hend Nabil Ellithy
مشرف / Walaa Abdelfattah Attya
تاريخ النشر
2017
عدد الصفحات
82 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
4/6/2018
مكان الإجازة
جامعة القاهرة - كلية الطب - Internal Medicine
الفهرس
Only 14 pages are availabe for public view

from 90

from 90

Abstract

Autoimmune Hemolytic Anemia (AIHA) is characterized by shortened red blood cell (RBC) survival and the presence of autoantibodies directed against autologous RBCs (Petz et al., 2004). Evan’s Syndrome is a combination between AIHA and Idiopathic or immune Thrombocytopenic purpura (ITP). B lymphocytes play important roles in the pathogenesis of AIHA/Evan’s syndrome. Recent studies have shown that CD5+B lymphocytes are associated with immune-related cytopenia and induction of apoptosis of CD5+b lymphocytes and down-regulation of activity of CD5+b lymphocytes can relieve this disease (Limin et al., 2005). In our study we investigate the expression of activation molecules on CD5+b lymphocytes in peripheral blood of autoimmune hemolytic anemia (AIHA)/Evan’s patients. Expression of activated molecules on CD5+b lymphocytes (CD86, CD69, HLA-DR) was performed using flow cytometry (Petz et al., 2004)