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Abstract Background: Diabetic neuropathies are a family of nerve disorders either subclinical or clinically evident that occurs in peripheral nervous system with type II diabetes. Currently, physical therapy treatment by low level laser therapy (LLLT) was found is effective in decreasing symptoms or even reversing the progress of tarsal tunnel syndrome (TTS). Purpose: the study aimed to find out the influence of the LLLT on the symptoms, neurophysiological study and visual analog scale (VAS) in type II diabetic patients with TTS. Method and Materials: thirty diabetic patients (14 women and 16 men) had TTS aged from 40 to 65 years were randomly selected and assessed neurophysiological study by analyzed motor and sensory (latency and amplitude) and VAS measured before, and after 12 weeks then received LLLT program along course of tarsal tunnel for 5 points each point received 120 second, time of all session 10 minutes. (Figure 18). Results: Statistical analysis showed that distal latency was significantly decreased by 23.39% (motor) and 29.67% (sensory), amplitude increased by 58.82% and VAS improved by 45.27% after LLLT sessions. Conclusion: LLLT influences the symptoms of TTS as a complication of type II diabetes mellitus |