الفهرس 
The relationship between daily sedative interruption and selected patients‘ outcomes among mechanically ventilated patients
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Abstract
Background: Mechanically ventilated patients are a risk group whose outcomes are negatively affected by many factors. Among these factors is sedation because sedation is a cornerstone therapy for critically ill patients. Aim of the study: to investigate the relationship between daily sedative interruption and selected outcomes of critically ill mechanically ventilated patients. Research Design: A descriptive correlational research design was utilized. Research questions: What is the relationship between daily sedative interruption and selected patients{u2019} outcomes among mechanically ventilated patients at ICUs of Cairo University hospital? Setting: different intensive care units of Cairo University Hospitals. Sample: A purposive sample of 80 critically ill patients connected to mechanical ventilators for at least 12 hours. Tools of data collection: four tools were utilized to collect data pertinent to the current study: tool 1: Personnel characteristics & Medical data sheet, tool 2: Richmond Agitation Sedation Scale (RASS), tool 3: Daily sedative interruption outcomes assessment tool, tool 4: Sequential Organ Failure Assessment score (SOFA score) . Results: The majority (72.5%) of the studied sample was males, and 43.8 % were in the age group of 50-{u2264} 60. More than one third received fentanyl as sedation. A significant statistical relationship was found between sedation name and ICU length of stay , sedation dose and ICU length of stay , RASS score and mechanical ventilation days (X²= 24.72, P value < 0.002) , (X²= 32.18, P {u2264} 0.008) , (X²= 10.63, P {u2264} 0.031) respectively . No significant statistical relationship was found between sedation name and the weaning type from mechanical ventilation (X²= 7.190.15, P < 0.126). No significant statistical relationship was found between sedation name and the occurrence of organ failure (X² = 3.29, P < 0.192)