الفهرس 
Label-free highly sensitive biosensors based on silicon on insulator
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Abstract
A highly sensitive hybrid plasmonic slot-waveguide (HPSW) biosensors based on silicon-on-insulator (SOI) are proposed and analyzed for DNA hybridization detection. The reported designs are based on increasing the light interaction with the sensing region by using slot-waveguide with plasmonic material. Due to the high index contrast and plasmonic effect, an ultra-high optical confinement is achieved in the low-index regions which enables the detection of the smallest change in the analyte refractive index with high sensitivity. The simulation results are calculated using full vectorial finite element method (FVFEM)