الفهرس 
ABO blood group genotyping and risk of hepatocellular carcinoma in cohort of Egyptian patients
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Abstract
ABO blood group genes are mapped at 9q34.2 region and a variety of polymorphisms has been reported in the ABO glycosyltransferase gene with more than 100 alleles, for the 4 ABO phenotypes, have been identified resulting from single nucleotide polymorphisms (SNPs) (Reid & Denomme, 2011). An association between ABO blood groups and some malignant cancers has been suggested in several studies which have revealed that blood group A increases the risk of cancer, including stomach (Song et al., 2013), ovarian (Poole et al., 2012), HCC (Li et al., 2012) and pancreatic (Wang et al., 2012) cancer. Non-O blood groups increase the risk of renal cell cancer (Joh et al., 2012), colorectal cancer (Urun et al., 2012) and skin cancer (Xie et al., 2010). Moreover an association between blood group B and gastric cancer was also reported (Etemadi et al., 2015). Several reports have indicated the involvement of ABO antigens as well as ABO locus in carcinogenesis. It was hypothesized that ABO antigens or ABO antigen expression might have implications for carcinogenesis in HCC and that blood group A might provide additional risk of HCC developmen