الفهرس 
Evaluation of middle cerebral/umbilical artery resistance and pulsatility indices ratio as predictors for fetal well-being and neonatal outcome in preeclampsia with or without IUGR
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Abstract
Background: To detect the accuracy of the middle cerebral to umbilical arteries Doppler indices ratio in predicting fetal well-being and neonatal outcome in pregnancies complicated by pre-eclampsia with or without evidence of intrauterine growth restriction. Methods: This study included 90 pregnant patients attending to Kasr El-Ainy Hospital high risk pregnancy unit from 2014 to 2016. Patients were divided into two groups, first group included 30 cases with normal uncomplicated pregnancies.The second group included 60 cases with pregnancies complicated by pre-eclampsia Patients of the pre-eclamptic group were subdivided further into two subgroups first is mild pre-eclampsia and second is sever pre-eclampsia and all subgroups were assessed for the presence of IUGR. Results:IUGR and adverse neonatal outcome were significantly associated with the severity of preeclampsia.The ability of CPR and R.I ratio to predict IUGR in mild group was evaluated; the sensitivity, specificity, positive predictive value, negative predictive value and accuracy for the CPR were 100%, 96%, 83.3%, 96% and 96.7% respectively. The corresponding figures for the RI ratio were 80%, 92%, 66.7%, 95.8% and 90%, respectively. Furthermore, in the sever group, the ability of CPR and R.I ratio to predict IUGR was evaluated ;the sensitivity, specificity, positive predictive value, negative predictive value and accuracy for the CPR were 94.4%, 100%, 94.4%, 92.3% and 96.7%. For detection of adverse neonatal outcome in the mild group, both CPR and R.I ratio showed similar values of sensitivity, specificity, positive predictive value, negative predictive value and accuracy of CPR and R.I ratio in detection of adverse neonatal outcome were 100%, 85.7% , 33.3%, 85, 7% and 86.7% respectively. where as in the sever group the sensitivity, specificity, positive predictive value, negative predictive value and accuracy of CPR and R.I ratio in detection of adverse outcome were 91.7%, 66.7%, 64.7%, 92.3%, 76.7% and 91.7%, 61.1%, 61.1%, 91.7% and 73.3% respectively