الفهرس 
Correlation between acute appendicitis and level of serum bilirubin
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Abstract
Background : The diagnosis of acute appendicitis is made using clinical findings and investigations. Recent studies have suggested that serum bilirubin, a simple biochemical test, is a positive predictor in the diagnosis of appendicular perforation and may be more specific than white cell count. The aim of this study to correlate between acute appendicitis and total bilirubin serum level as a valid biomarker for prediction of complication.Patients and Methods: This prospective study conducted on 150 patients underwent appendectomy in Kasr-alainy medical school hospitals, Cairo University from October 2017 till March 2018. We assessed sensitivity, specificity, and positive and negative predictive value of total serum bilirubin levels in acute appendicitis.Results: The sensitivity of the total serum bilirubin as a predictor for complication in acute appendicitis was found to be 82% with the NPV = 94.19%, and the specificity was 94.19 .3% while PPV = 82.76.%. while the sensitivity of WBC levels with cut off value of 14.2 x 103 was found to be 72.4% .Conclusion: Total serum bilirubin, in this study, proved to be highly accurate and sensitive in predicting complication of acute appendicitis. Therefore, patients with clinical signs and symptoms of appendicitis and with hyperbilirubinemia should be identified as having a higher probability of appendicular perforation. Total serum bilirubin appears to be a new promising laboratory marker for diagnosing appendicular perforation