الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 71 |  |  |
| | | from | 71 | | |
Abstract
Ischemic heart disease is one of the leading causes of death all over the world. Coronary heart disease is caused by many pathological mechanisms that lead to blood supply demand mismatch. Atherosclerosis is the most common mechanism and has many complications like arterial stenosis, thrombosis and atheromatous plaque formation.
Ischemic heart disease is usually a symptomatic disease with many patterns of symptoms including most commonly chest pain, dyspnea, and epigastric pain and other uncommon symptoms. This is recently defined chronic coronary syndrome (CCS), when these symptoms occur with effort. Usually medically treated, but when there is a significant coronary artery stenosis, it may need a percutaneous coronary intervention and stent implantation.
In-stent restenosis is one of the common outcomes after PCI; it is responsible for the occurrence of CCS. It is mainly detected by ICA as the gold standard in diagnosis. The pathology of ISR is believed to be due to neoatherosclerosis that causes arterial luminal narrowing.
CCTA is now considered a reliable tool of ISR diagnosis, as the new generation CT devices, with its high resolution and quality of images, are capable of visualizing stent lumen and detection of luminal narrowing or total occlusion.
The aim of this work is to study the outcomes of percutaneous coronary intervention in patients who develop symptoms of coronary artery disease by using the coronary computed tomography angiography.
In the present study, we had screened 51 symptomatic patients retrospectively from the beginning of February 2016 until the first of January 2020 and prospectively from the beginning of February 2020 till the end of February 2021. They were evaluated both by CCTA and ICA. The retrospective group was followed up for a period of 4 years and the prospective group for 11 months for the development of major adverse cardiovascular events. All of them were screened for traditional cardiovascular risk factors.
In the 51 consecutive patients, where there were 44 males (86.3%) and 7 females (13.7%). The age ranged from 35 to 71 years with a mean age of 58.1 ± 7.94 years.
In the present study, the symptoms by which the studied patients presented were mainly anginal chest pain and dyspnea (100% and 21.6% respectively).
Overall, 94.1% of patients were hypertensive, which is the most common risk factor. Ninety percent of patients were having dyslipidemia, and is considered the second most common risk factor in the studied