الفهرس 
PRETERM LABOROnly 14 pages are availabe for public view
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Abstract
Background: The prediction of preterm birth (PTB) is important in the management of
symptomatic preterm labor women. We evaluated the effectiveness of the fetal fibronectin
(fFN) test for predicting PTB in symptomatic preterm labor women with consideration of
physiologic changes in cervical length (CL) and uterocervical angle (UCA) during pregnancy.
Objectives: to predict the onset of labor in women who present with PTL through cervical
assessment [cervical length (CL) & uterocervical angle (UCA)], and Cervicovaginal fetal
fibronectin (FFN) as a marker for premature labor (PTL).
Methodology: A prospective cohort study was carried out on 90 symptomatic women at
high risk of preterm labor (PTL), attending the Gynecology and Obstetrics department at
Fayoum University Hospital, fFN in cervicovaginal fluid was assessed by ELISA technique,
Uterocervical angle and cervical length were measured by transvaginal ultrasound. Maternal
history and pregnancy data were recorded. Delivery data were subsequently collected.
Results: In the current study we included 90 women with symptoms of sPTB, with an average
age of (21.79 ±3.3) years old, an average BMI of (24.6 ±5.8) kg/ m2 and an average GA of
(32.83 ±2.3) weeks. There were 12 women in our cohort reported previous preterm labor. CL
and
fFN showed better sensitivity and specificity as compared to UCA. Logistic regression analysis
demonstrated that the sPTB in the current cohort was only dependent on the cervical length and
quantitative fFN at the time of presentation.
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ABSTRACT
Conclusions: That the combination of fFN, CL and UCA could improve
PTB prediction accuracy, especially with the focus on the CL and fFN level it could
help clinicians identify the women at risk of delivery before 34 weeks or 37 weeks.
Key Words: Uterocervical Angle, Cervical Length, Cervicovaginal Fetal Fibronectin (FFN),
Symptomatic Preterm Labor.