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العنوان
Neutrophil/lymphocytes and platelets/lymphocytes ratios As inflammatory markers in children with attention –deficit hyperactivity disorder /
المؤلف
Fathi, Walaa Esam Mohamed.
هيئة الاعداد
باحث / ولاء عصام محمد فتحي
مشرف / محمد فاروق عفيفي
مشرف / مروه ولي الدين علي
مشرف / اسماء خلف الله كامل
الموضوع
Pediatrics.
تاريخ النشر
2023.
عدد الصفحات
91 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة المنيا - كلية الطب - طب الأطفال
الفهرس
Only 14 pages are availabe for public view

from 92

from 92

Abstract

Thought Deficiency Hyperactivity Problem (ADHD) is a neurodevelopmental issue which cause near and dear and direct issues. The three essential symptoms of ADHD which are distractedness, hyperactivity, and lack of caution, regularly appear in kids before the age of 12 years old and can go on until the young person shows up at adulthood (Faraone et al., 2015, American Mental Association,2013). the neutrophil/lymphocyte extent (NLR), platelet/lymphocyte extent (PLR), monocyte/lymphocyte extent (MLR), and mean platelet volume (MPV) have actually been used as characteristics of a basic red hot response ,which could expect a section in the etiopathogenesis of ADHD(Önder et al., 2021)
The place of this study was to evaluate Total blood picture limits as markers in ADHD earnestness of children, and to survey Total blood picture limits values in gauge of treatment response in young people with ADHD.
The children associated with the audit were detached as following:
Bundle 1: 40 children, broke down as ADHD from adolescents who had standard advancement in the Pediatric Neuro mental Short term Center of Minia College Youngsters and Maternity Medical clinic. Their age went from 6 to 18 years.
They were also parceled to the going with get-togethers:
Pack 1A: included 20 as of late broke down children to have ADHD preceding taking any clinical treatment f ADHD. , they were (90%male, 10%female) with age range(6-15),and Mean ± SD = 8.15 ± 2.62
Pack 1B: included 20 as of late examined children to have ADHD and they were under treatment with non catalyst ADHD remedy for somewhere near a half year they were (70%male, 30%female) with age range(6-12),and Mean±SD= 8.15 ± 1.62
Bundle 2: 20 obviously sound children with matched age and sex to pack І young people. they were (65%male, 35%female) with age range(6-12),and Mean ± SD= 9.15 ± 1.59
The principal outcomes of the audit uncovered that:
that Neutrophils/lymphocytes extent was on a very basic level higher in un-relieved and calmed bundle than the controlled assembling( p= 0.0001,.006 independently), in like manner there was no huge differentiation among quieted and un-restored bundles as regard Neutrophil/Lymphocyte extent( p value= 0.121).
Monocytes/lymphocytes extent was basically higher in the un unendingly quieted bundle than control pack with (p regard = 0.0001, 0.001)respectively ,While it was out and out higher in unmedicated pack than relieved group(1B) ( p regard =0.031).
Platelet/lymphocytes extents was out and out higher in unmedicated bundle appeared differently in relation to control pack ( p value=0.004).
Of course there is no colossal differentiation among calmed and control groups(2) ( p regard = 0.317) similarly there was no monstrous qualification some place in the scope of unmedicated(1A) and medicated(1B) get-togethers( p value=0.138).
Also we found that gigantic positive association between’s CBC provocative extents ( neutrophil/lymphocyte, monocyte/lymphocyte extents,) and ADHD Conner’s score ,which could reflect the occupation of CBC red hot markers as signs of ADHD disease reality and treatment response.