الفهرس 
COVID-19Only 14 pages are availabe for public view
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Abstract
Background: Multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19 is a rare complication of (SARS-CoV-2) infection. Presenting (4–6) weeks after infection as high fever, organ dysfunction, and strongly elevated markers of inflammation which is mostly due to post infection immune reaction.
Aim of the work: to evaluate cardiac outcomes 6 months after initial presentation with MIS-C associated with cardiac affection.
Patients and Methods: This was a retrospective cohort study on 28 patients (19 boys & 9 girls) who were diagnosed as multi system inflammatory syndrome in children (MIS-C) related to COVID19 six months ago at children`s hospital, Ain shams university from January 2021 to October 2021. All patients were subjected to the following: (demographic data, clinical signs and symptoms, laboratory investigations) in the acute phase (obtained from patient’s medical records) and at follow up after 6-months.
Results: in our study all patients fulfilled criteria of MIS-C presented with fever with shock or cardiac dysfunction and gastrointestinal symptoms in addition to conjunctivitis and skin rash. Our patients were presented with hypotension with mean systolic blood pressure (87) mmHg & mean diastolic blood pressure (48) mmHg. Regarding symptoms: vomiting was seen in (60.7%), diarrhea in (32.1%), conjunctivitis in (82.1%) and cardiovascular abnormalities were seen in (100%) in the form of (myocardial dysfunction, coronary dilatation, valvular regurgitation and pericardial effusion). After 6 months there was significant improvement regarding vital signs. Regarding laboratory findings: at time of presentation most of the patients had high CRP, high troponin, and high CK-MB. On follow up after 6 months, all patients had normal values.
Conclusion: Our follow up study suggests that functional recovery and coronary outcomes are good in multisystem inflammatory syndrome in children