الفهرس 
Clinicopathological features and surgical management of primary extra-adrenal neuroblastoma
ABSTRACTOnly 14 pages are availabe for public view
 |  | from | 267 |  |  |
| | | from | 267 | | |
Abstract
Background: Neuroblastoma (NB) is the most common and deadly extra cranial solid tumor of childhood. It is a malignant tumor of neural crest origin that most commonly originates in the adrenal medulla or the paraspinal sites where sympathetic nervous system tissue is present Methods: Patients with neuroblastoma presenting to children{u2019}s cancer hospital from 1st of January 2008 to end of December 2011 and Patients underwent stratification according to risk into low, intermediate and high risk, all patients enrolled in this study will be analyzed for clinicopathologic features. Results: Out of 421 cases 262 were adrenal neuroblastoma and 159 were extraadrenal. Surgical resection was attempted in 282 patients ,50% were complete or near complete excision and the remaining either more than 90% or 50-90% or less than 50% resection. In this study stage of disease was strongly and significantly related to overall survival with a poorer survival in late stages (stage IV) as compared to stage I and stage III. And extent of surgical resection was also significantly related to overall survival with better survival in cases who underwent complete or near complete resection