الفهرس | Only 14 pages are availabe for public view |
Abstract Obstructive sleep apnea (OSA) is a chronic respiratory disorder with a high and increasing prevalence. OSA is characterized by intermittent upper airway collapse and reopening during sleep, leading to intermittent hypoxemia during sleep which increases the production of reactive oxygen species and pro-inflammatory mediators. Oxidative stress and inflammation generate endothelial dysfunction, cardiovascular diseases such as arterial hypertension, coronary ischemia, and lung inflammation. Recently, numerous studies have demonstrated that surgical patients with sleep apnea are at increased risk of having perioperative complications, including hypoxemia, pneumonia, difficult intubation, myocardial infarction, pulmonary embolism, atelectasis, cardiac arrhythmias, and unanticipated admission to the ICU |