الفهرس 
Nosocomial Clostridium difficile-associated diarrhea in Children?s Hospital, Cairo University
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Abstract
To assess frequency of clostridium difficile as a cause of nosocomial diarrhea and to determine the risk factors associated with the development of clostridium difficile associated diarrhea (CDAD) in Cairo university children hospitals, Egypt. In this descriptive cross-sectional study, 70 children developed nosocomial diarrhea between October 2015 and February 2016. A medical history, clinical assessment and culture for Clostridium difficile and direct toxin detection from stool samples by enzyme immuno-assay were undertaken in all patients. Only 4 (5.7%) of studied patients were found with positive C.diffcile toxin A/B detection by ELISA, fever and abdominal distension were significantly higher in patients with CDI than other causes of ND, no significant difference between patients with CDI and other causes of ND as regards to antibiotics used before appearance of diarrhea and risk factors. Clostridium difficile is a significant cause of nosocomial diarrhea. Antibiotic use was a risk factor for CDAD