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العنوان
FGF23 in incident haemodialysis patients, levels and correlation with vascular calcification /
الناشر
Wessam Abdelrahman Sherif ,
المؤلف
Wessam Abdelrahman Sherif
هيئة الاعداد
باحث / Wessam Abdelrahman Sherif
مشرف / Usama Abdalazeem Sharaf Aldeen
مشرف / Noha Adel Ibrahim Osman
مشرف / Mohammed Mahmoud Hassan Elsebaie
تاريخ النشر
2014
عدد الصفحات
86 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب الباطني
تاريخ الإجازة
15/3/2017
مكان الإجازة
جامعة القاهرة - كلية الطب - Internal Medicine
الفهرس
Only 14 pages are availabe for public view

from 97

from 97

Abstract

During the past decade many factors such as age, systolic blood pressure, hyperphosphatemia and fibroblast growth factor 23 (FGF23) have been addressed as causes of vascular calcification and hence of increasing morbidity and mortality among haemodialysis patients. FGF23, a phosphaturic factor produced by osteoblasts has emerged as a major regulator of mineral metabolism in health and disease. Under physiological conditions, it acts as a circulating phosphaturic factor through suppression of proximal tubular Na / Pi-2c co transporters. FGF23 together with its cofactor Klotho have been found to be expressed and FGF23 to be elevated in patients on haemodialysis