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العنوان
Vitamin D in patients with Behçet{u2019}s disease /
الناشر
Zeinab Alhussien Mohamed Alnahas ,
المؤلف
Zeinab Alhussien Mohamed Alnahas
هيئة الاعداد
باحث / Zeinab Alhussien Mohamed Alnahas
مشرف / Gaafar Mohamed Ragab
مشرف / Manal Mohamed Abdelmoniem Elmenyawi
مشرف / Olfat Gamil Shaker
تاريخ النشر
2016
عدد الصفحات
125 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب الباطني
تاريخ الإجازة
9/3/2016
مكان الإجازة
جامعة القاهرة - كلية الطب - internal medicine
الفهرس
Only 14 pages are availabe for public view

from 136

from 136

Abstract

Behcet{u2019}s Disease is a chronic inflammatory disease characterized by recurrent orogenital ulcerations, ocular manifestations, arthritis, and vasculitis. The etiology and pathogenesis of Behcet{u2019}s Disease have not been clearly defined. Vitamin D has major biologic activities including cellular proliferation and differentiation, immune system modulation and muscle strengthening. It also may be an environmental factor important in the etiology of T-cell-mediated autoimmune diseases.VDR gene contains more than 470 single nucleotide polymorphisms, which cause functional differences in immuno-modulatory action of vitamin D. The most common polymorphisms of the VDR include FokI and BsmI