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العنوان
Stability indicating method for determination of drugs containing ester group /
الناشر
Mai Mohamed Abdelaziz ,
المؤلف
Mai Mohamed Abdelaziz
هيئة الاعداد
باحث / Mai Mohamed Abdelaziz
مشرف / Laila Elsayed Abdelfattah
مشرف / Hayam Mohamoud Lotfy
مشرف / Maha Abdelmonem Hegazy
تاريخ النشر
2016
عدد الصفحات
187 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
Analytical Chemistry
تاريخ الإجازة
19/6/2017
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Analytical Chemistry
الفهرس
Only 14 pages are availabe for public view

from 280

from 280

Abstract

Esters mainly result from the condensation of a carboxylic acid and alcohol. Hydrolysis of esters into their respective organic acid and alcohol alkali and acid. This thesis is concerned with the analysis of two selected drugs which containing ester groups namely Nicardipine Hydrochloride from anti- hypertensive class and Pravastatin Sodium from anti-hyperlipidemia class. In this work different stability indicating methods were developed for the determination of Nicardipine and Pravastatin in the presence of their alkali induced degradation products and in dosage forms using spectrophotometric and chromatographic techniques which would be feasible, sensitive and specific