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Abstract Background: Mechanical ventilator has serious complications, so the ultimate goal of mechanical ventilation is ventilator discontinuation. Ventilator bundle is a group of practices developed by IHI aiming to improve the patient outcomes. Aim of the study: examine the relationship between the implementation of ventilator bundle practices and weaning among mechanically ventilated patients at a selected private health care sector. Research design a descriptive co- relational design was utilized. Sample: Purposive sample of 60 mechanically ventilated patients divided into two groups. The first group includes patients for whom all elements of the ventilator bundle are applied completely, while the second group includes patients for whom the ventilator bundle elements are not done completely. Setting: This study was done at the Intensive Care units of a selected private hospital in Cairo. Tools of data collection: Three tools were utilized: socio-demographic and medical data sheet, ventilator bundle compliance checklist, and burns’ wean Assessment Program (BWAP) checklist. Results: There is significant positive correlation between ventilator bundle compliance score and weaning from mechanical ventilator (r =0.57, p=0.0001).There was significant statistical difference between compliant group and non-compliant group regarding weaning indicator scores were (t=4.20; p=0.001). There was significant difference between patients of the two groups regarding the compliance with individual ventilator bundle elements as regards head of bed elevation head of bed elevation (x2=5.01 ,p= 0.04), sedation interruption (x2=6.4,p=0.03) and assessment of readiness to extubate (x2= 5.2, p=0.02 ). Conclusion: implementing ventilator bundle not only helps in VAP prevention, but also plays a pivotal role in weaning from mechanical ventilator |