Search In this Thesis
   Search In this Thesis  
العنوان
Correlation of endothelial function with oxidative dna damage in obesity and metabolic syndrome /
الناشر
Zeinab Abdelatif Mohamed Sabra ,
المؤلف
Zeinab Abdelatif Mohamed Sabra
هيئة الاعداد
مشرف / Zeinab Abdelatif Mohamed Sabra
مشرف / Rokia Abdelaziz Mohamed
مشرف / Sahar Abdelaty Sharaf
مشرف / Mary Wadie Fawzy
مشرف / Noha Khalil Mohamed
تاريخ النشر
2016
عدد الصفحات
171 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب الباطني
تاريخ الإجازة
16/9/2016
مكان الإجازة
جامعة القاهرة - كلية الطب - internal medicine
الفهرس
Only 14 pages are availabe for public view

from 204

from 204

Abstract

Background: Obesity is a condition where a person has accumulated so much body fat that it might have a negative effect on their health. Metabolic syndrome is a term for a group of conditions, including high blood pressure, high blood sugar and high cholesterol levels, that when combined increase an individual’s risk of developing coronary heart disease, stroke and diabetes. Endothelial dysfunction is a well established response to cardiovascular risk factors and precedes the development of atherosclerosis. Oxidative stress (OS) is involved in pathological processes such as obesity, diabetes, cardiovascular disease, and atherogenic processes. Objectives: Assessment of 8-oxodG (oxidative stress biomarker) in obesity and metabolic syndrome and study its relationship to atherosclerosis in obese patients with and without metabolic syndrome. Methods: 52 obese with and without metabolic syndrome will be assessed to levels of 8-oxodG, CIMT and ABI and the results will be compared to 31 healthy controls