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Abstract
BACKGROUND: Stem cell transplantation (SCT) has been the treatment of choice for patients with a variety of hematological Diseases; however, BMT is associated with transplant-related functional impairment, which compromise full rehabilitation. AIM: The purpose of this study was designed to determine the efficacy of therapeutic exercise on patients after stem cell transplantation. DESIGN: Randomized controlled clinical trial. Subjects and Methods: Thirty patients who had severe aplastic anemia after stem cell transplantation, their ages were ranged from 18-40 years. Patients were recruited from BMT Unit at Nasser Institute Hospital, Ministry of Health. Between Jan 2016 and May 2016. They were divided randomly into 2 equal groups; group A (study group) received exercise program in the forms of aerobic exercise, chest physiotherapy and gait training by early ambulation (30 minutes / session, three sessions / week for five weeks) in addition to routine medical care and group B (control group) received routine medical care only and not received any therapeutic exercise program. Patients were evaluated for their fatigue by Iowa fatigue scale (IFS) and Complete Blood Count test (CBC) before and after five weeks of administration of program. RESULTS: Independent t-test to compare post treatment test revealed that there was significant difference of IFS, Hb and Platelets count between the both groups with better improvement in group A (p<0.05). CONCLUSION: the therapeutic exercise had an instantaneous effect on different complications after bone marrow transplantation of patients with severe aplastic anemia. Effectiveness of exercise therapy as important part 1 management to increase the ability to maintains the functional capacity and raise quality of life that lead to improve rate of the deterioration in health status that can affect multiple aspects of patients, life in cases of bone marrow transplantation. This finding of the current work is an agreement with the previous studies and past literatures