الفهرس 
Anatomy of the lungs and mediastinumOnly 14 pages are availabe for public view
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Abstract
Background: Lung cancer is the most commonly diagnosed cancer; of which the non-small cell lung cancer (NSCLC) accounting for approximately 80% of the newly diagnosed lung cancer. The prognosis of lung tumors depends on early and accurate staging as well as the histopathological type of the tumor. It is suggested that NSCLC with different pathological types and sizes can produce variable max.SUV values on (18F-FDG) PET/CT with different lymph nodes and distant metastatic potential.
In this study, we aim to evaluate the relationship between the maximum SUV measured on (18F-FDG) PET/CT with tumor pathological type, tumor size, lymph node metastasis and distant metastasis in patients with NSCLC.
Results: The study included a retrospective analysis of the fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) findings of 40 patients with NSCLC. Statistical analysis was used to determine the correlation between max.SUV and tumor size, with each pathological type, nodal (N) staging and distant metastasis (M) staging. The primary lung tumors histopathological types were 25 (62.5%) adenocarcinomas, 12 (30%) squamous cell carcinomas and 3 (7.5%) large cell carcinomas. The max. SUV and tumor size of the squamous cell carcinoma group was significantly higher than that of adenocarcinoma and large cell cancer groups (P= 0.000009). A significant positive correlation was found between the primary tumor Max.SUV and tumoral size. Neither lymph node nor distant metastases involvement were correlated with tumor max.SUV.
Conclusions: The tumor size and histologic subtype both strongly influence FDG uptake in lung cancer. Nonetheless, Max.SUV is not predictive of the presence of metastases or lymph node involvement.