الفهرس 
AcknowledgementOnly 14 pages are availabe for public view
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Abstract
1- Simultaneous estimation of recently FDA approved co-formulated ophthalmic solution benoxinate and fluorescein: Application to aqueous humor. Published in Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 267, p.120599. (Q1 - Impact factor: 4.831) 2- A highly sensitive spectrofluorimetric method for the determination of bilastine in its pharmaceutical preparations and biological fluids. Published in Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 286, p. 121246. (Q1 - Impact factor: 4.831)
Papers submitted for publication 3- Green fluorometric strategy for simultaneous determination of the antihypertensive drug and COVID-19 candidate Telmisartan with Nebivolol in human plasma Under review in Scientific Reports Journal. (Q1 - Impact factor: 4.379)
LIST of PUBLICATIONS
List of publication
4- Study of the binding interaction of salmon sperm DNA with nintedanib, a tyrosine kinase inhibitor using multi-spectroscopic, thermodynamic, and in silico approaches Submitted to International Journal of Biological Macromolecules. (Q1 - Impact factor: 8.025)
5- Green one-pot synthesis of carbon quantum dots as new fluorescent nanosensors for determination of meloxicam in dosage forms and biological fluids: application to content uniformity testing Submitted to Microchemical Journal. (Q1 - Impact factor: 5.304)
The aim of this thesis was to develop sensitive and reliable advanced techniques for the analysis of some pharmaceutically important compounds containing heterocyclic rings
Different methods of analysis were investigated for the determination of the studied compounds in raw materials, multi-component dosage forms and biological fluids. The usefulness of different spectrophotometric, spectrofluorimetric and chromatographic methods were exploited. This thesis included a study of the experimental parameters that may affect the sensitivity, accuracy, and precision of the developed methods. Comparative studies between the results of the developed methods and those of reported methods were carried out.
These groups of compounds are extensively prescribed in the local and international market and so there is a great need to develop more simple, accurate and precise methods for their analysis. The developed methods can be applied in quality control laboratories in pharmaceutical companies. This thesis is focused on the analysis of different categories of drugs which are Meloxicam, Nebivolol, Telmisartan, Bilastine, Benoxinate, Fluorescein and Nintedanib in different dosage forms