الفهرس 
COVID-19Only 14 pages are availabe for public view
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Abstract
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and was declared a global pandemic in March 2020.
Pregnant women are particularly vulnerable to respiratory pathogens and severe pneumonia due to physiological and immunological changes, such as altered T lymphocyte immunity, increased oxygen consumption, decreased functional residual capacity and decreased chest compliance, which may result in higher maternal and fetal morbidity and mortality.
Previous studies on influenza infection during pregnancy found adverse pregnancy outcomes including higher rates of preterm birth (PTB) and caesarian delivery in women infected during late pregnancy. Other Coronaviruses such as severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) have been associated with excess risk for preterm delivery and spontaneous abortion.
Pregnant people infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may be asymptomatic or symptomatic. Those who are symptomatic appear to be at increased risk for developing severe sequelae of coronavirus disease 2019 (COVID-19) compared with nonpregnant reproductive-aged females. They also may be at increased risk for developing some pregnancy complications (eg, preterm birth) compared with uninfected or asymptomatic pregnant people.
In utero transmission is rare, rates of miscarriage and congenital anomalies do not appear to be increased in pregnancies affected by COVID-19, and neonatal outcome is generally good.
The aim of the present study was to determine the outcome of pregnancy for cases of infection with the Covid 19 during pregnancy.
This was Retrospective study, was carried out Isolation hospital in Faculty of Medicine, Benha, qalyubia during pandemic from 2/2020 to 2/2022, on pregnant women with Covid 19 with +ve PCR. All patients were subjected to: history taking, complete general examination, abdominal examination, and Ultrasound evaluation.
The main results of the study revealed that:
The mean age of studied cases was 29.53(±4.21 SD) with range (22-36), among the studied cases there were 19 (31.7%) nulipara, 14 (23.3%) with parity of 1and 37 (61.7%) with parity more than, there were 3 (5%) with previous abortion and 4 (6.7%) with history of preeclampsia.
The mean BMI of studied cases was29.44 (±2.02 SD) with range (25.8-33.2).
Among the studied cases there were 4 (6.7%) with diabetes and 5 (8.3%) with hypertension.
Among the studied cases there were 45 (75%) with fever, 41 (68.3%) with dry cough, 29 (48.3%) with fatigue, 23 (38.3%) with dyspnea, 7 (11.7%) with diarrhea and 2 (3.3%) with headache and there were 15 (25%) who needed ventilation.
According the severity of disease there were42 (70%) moderate cases and 18 (30%) severe cases.
The mean Hb of studied cases was 11.17 (±1.46 SD) with range (8.8-13.6), the mean WBCs was 6.54 (±2.32 SD) with range (3-10.9),the mean PLTs was 210.25 (±32.1 SD) with range (141-267),the mean ALT was 44.58 (±34.16 SD) with range (8-127),the mean AST was 41.4 (±32.13 SD) with range (7-128) and the mean CRP was 44.07 (±59.65 SD) with range (4-59.65).
The mean gestational age of studied cases was 35.58(±2.82 SD) with range (28-39), all the studied cases had cesarean section and 15 (25%) maternal death.
Among the studied cases there were 9 (15%) with IUGR, 44 (73.3%) who needed NICU and 6 (10%) neonatal death.
Based on our results we recommend for further studies on larger patients and longer period of follow up to emphasize our conclusion.