الفهرس 
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Abstract
Summary & Conclusion
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, sputum production) due to abnormalities of the airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that cause persistent, often progressive, airflow obstruction. (Celli B et al, 2022).
Sleep is a normal physiological process that is of great importance to us all. (Hall, 2015)
The aim of the work was to detect sleep pattern changes in COPD patients.
The study was conducted at Chest Department in Beni-Suef UniversityHospitals on 75 individuals during the period from February 2022 and December 2022., divided into 2 groups, the first is the study group included 50 COPDpatients And second group is the controlled group, it included 25apparently healthy individuals.
Inclusion criteria
All patients aged >forty years and < eighty years, of both gender who diagnosed to have COPD according to GOLD 2022 by spirometry and given the consent for participation in the study.
Exclusion criteria
1- Patients who refused to participate in the study.
2- patients who failed to perform pulmonary function test due to acute exacerbation or severe illness.
3- patients unable to tolerate whole-night polysomnography.
4- patients disqualified from polysomnography, and pregnant women.
5- chronic obstructive pulmonary disease with end organ failure.
6- COPD patients during exacerbation.
7- History of intake of drugs affecting sleep quality e.g., hypnotics and depressants.
All individuals (diseased group 1and control group 2) were admitted in the Chest Department and underwent the following: History taking, and examination was done, BMI calculations, arterial blood gases analysis, Pulmonary function tests, unattended polysomnography that was conducted in the sleep unit of the chest department, Beni-SuefUniversity. They should abstain from caffeine in the afternoon and evening of the day of the study, avoid alcohol, strenuous exercise, also avoid naps on the day of the study. All patients continue their usual medications on the night of the study, recorded by the technician to help in interpretation.
Among the 75 cases studied, the mean age in the COPD group was 61.6±8.5 and the mean age in the controlled group was 62.3 ±8.5, there were 19 females and 31 males COPD patients and there were11females and14 males in the control group, the mean BMI in COPD patients was 30.9 ±6.4 and in the controlled group was 29.5 ± 3.64.
Regarding sleep pattern parameters that there was a statistical significant difference with p-value <0.05 between AHI degree with higher percentage of mild, moderate, and sever degree of AHI index levels among cases. On the other hand, there was no statistical significant difference with p-value >0.05 as regards apnea types.
In this study,there was a statistical significant higher mean of arrhythmia number, and index among cases with p-value 0.001. In addition, there was a significant higher mean of PLM and PLM index among cases with p-value <0.001.
In this study, there is significant difference between COPD patients and the controlled group regarding mean of desat. scores (number and desat. index) among cases with p-value <0.05.
In this study,there was a statistical significant higher percentage of hypertension and sever degree of dyspnea with p-value <0.001 among sever degree of AHI.
In this study; there was a statistical significant lower mean of FEV1/FVC, FEV1, and 6MWT, and a higher mean of ESS, and Stop questionnaire with p-value <0.001, 0.02, 0.002, <0.001, and <0.001 respectively among cases with sever degree of AHI.
In our study, there was statistical significant positive correlation with p-value <0.05 between AHI score and each of FVC, Stop questionnaire, and ESS.
In our study, there was a statistical significant negative correlation with p-value <0.05 with FEV1/FVC, FEV1, and 6MWT.