الفهرس 
Genotypes and virulenceOnly 14 pages are availabe for public view
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Abstract
Toxoplasma gondii (T. gondii) is a widespread intracellular protozoan parasite of animals that causes zoonotic infections in humans. T. gondii infection causes encephalitis, brain abscesses, and death in immunocompromised patients (Wang et al., 2017b). Moreover, congenital T. gondii infection of the fetus can cause ocular and neurological impairment or it may lead to abortion (Hampton, 2015). The standard therapy for toxoplasmosis is the anti-folate combination of pyrimethamine and sulfadiazine. However, these drugs may cause several toxic side effects which are intolerable to the patients (Alday and Doggett, 2017). Therefore, the study of new therapeutic strategies for toxoplasmosis is necessary, for example, the repurposing of medicines. Mefloquine (MQ) is an antimalarial medicine that has been repurposed. It is proven to have protective effects against apicomplexan parasites such as Babesia and Cryptosporidium parvum (Munkhjargal et al. 2012; Aly et al. 2017).