الفهرس 
Interstitial Laser treatment of Primary Axillary Hyperhidrosis: A comparative study between 980 nm. and 1470 nm. diode lasers
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Abstract
Background: primary axillary hyperhidrosis (PAH) is a distressing condition that can pose significant social embarrassment. The different treatments of (PAH) such as topical agents, systemic agents, and botulinum toxin are only temporarily effective and still in a great need for evidence-based management. The following study describes a new technique for relieving problems in the management (PAH). We study the efficacy and safety of two different diode lasers, at 980 nm or 1470 nm, subdermalapplication of pulsed garnet laser for ablation of the sweat glands versus intradermal Botulinum toxin A (BTA) in the management of PAH.
Patients and methods: This parallel-randomized controlled pilot study was conducted upon 90 PAH patients from December-2019 to November-2021; the diode laser 980 nm group (30 cases), the diode laser 1470 nm group (30 cases) and the BTA group (30 cases).
Results: The three groups were comparable regarding age, BMI, and gender. The laser groups had higher reduction of HDSS score than the BTA group at 1-month 1.37±0.49 and 1.20±0.41 versus 2.03±0.67 for the laser 980, the laser 1470 and the BTA groups, respectively (p-values < 0.001) and at 6-months (1.37±0.48 and 1.20±0.41 versus 2.20±0.55; p-value < 0.001). At 1-month and 6-months, the laser groups had higher reduction of mean moisture percentages than the BTA group at 1-month with 49.34±5.88% and 48.93±6.62% versus 55.89±9.20%, respectively (p-values 0.003 & 0.001) and at 6-months 49.42±6.32% and 48.90±6.79% versus 56.21±7.98%, respectively (p-values 0.001 &< 0.001).
At 1-month and month-6, there was a higher patient satisfaction in the laser groups than in the BTA group (p-values < 0.05). The laser groups demonstrated significantly better GAISscore than the BTA group at both 1-month (p-values < 0.05) and 6-months visits (p-values < 0.001).
Conclusion: The current study showed that Diode laser 1470 nm is a safe and an effective treatment for PAH more than Diode laser 980 nm.