الفهرس 
A Comparative Pharmacognostical Study on Citrus medica var. sarcodactylis Swingle (Buddha,s hand) and Limonia acidissima Linn. (Feronia), Family Rutaceae Cultivated in Egypt
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Abstract
Citrus medica var. sarcodactylisand Limoniaacidissima are plants belonging to family Rutaceae. GC/MS analysis of the essential oils resulted in identification of twenty-one components accounting for (98.51%) identified in fruits oil of Citrus medica, while from its leaves oil fourteen components were identified representing(92.69%) of the total oil. The major component is limonene for both fruits and leaves oil representing (60.31% and 32.11%) respectively. While the oil of the leaves of Limoniaacidissima L. prevealedeight components were identified representing (97.9%) and the major component is carvacrol (71.15%). HPLC analysis of the crude methanol extract of C. medica var.sarcodactylisfruits and leaves revealed the identification of 12 and 13 compounds respectively. L.acidissima fruits nine compounds were identified while its leaves methanol extract shows twelve compounds. Rutin is present in leaves extract of both plants as a major compound. Also, P-hydroxy benzoic acid is present in fruits and leaves extracts of both plants in high concentration. While, Crude methanol extracts of C. medica var.sarcodactylisand L. acidissimawere analyzed via high resolution UPLC–ESI–QTOF–MS-MS in negative and positive ionization mode resulted in a total of48 & 74 chromatographic peaks respectively belonging to various metabolite classes.GC/MS analysis for USM and FAMErevealed comparable number of compounds in both plants under investigation. The identification of 39 compounds representing (89.85%) of the total USM of C.medica leaves ,34 compounds representing (83.53%) of the total USM of L.acidissimaleaves and 35 compounds of the total USM of L. acidissima fruits representing (89.69%) and for FAME identification of 12,4 and18 compounds account for (88.05, 50.96 and 96.97%) for C. medica leaves, L. acidissimaleaves and fruits respectively. Isovitexinwas isolated and identified from the ethyl acetate extract of L. acidissima leaves.while β- Sitosterol was isolated and identified from L. acidissima fruits and also ferulic acid, p-coumaric and vanillic acid were isolated fromL. acidissima leaves. Essential oils, crude methanol extracts and successive fractions of each plant part were tested for their antimicrobial and antiviral activities.