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العنوان
Cardioprotective Effect of Propofol in Cardioplegia Compared to Systemic Propofol in Heart Valves Surgery :
المؤلف
Attia, Amr Atef Sayed Ahmed Mahmoud.
هيئة الاعداد
باحث / عمرو عاطف سيد احمد محمود عطية
مشرف / عبد الهادى محمد طه
مشرف / ايهاب عبد المنعم وهبى
مشرف / محمد محمود ابو النصر
الموضوع
Cardiothoracic Surgery.
تاريخ النشر
2023.
عدد الصفحات
137 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
جراحة
تاريخ الإجازة
26/3/2023
مكان الإجازة
جامعة طنطا - كلية الطب - Cardiothoracic Surgery
الفهرس
Only 14 pages are availabe for public view

from 184

from 184

Abstract

Myocardial protection is still a focus of ongoing researches and cardioplegia is still the main appropriate way for cardiac arrest during cardiac surgery with cardiopulmonary bypass and it plays a very important role in myocardial protection strategies. Several additives have been added to the cardioplegia to enhance the myocardial protection but the ideal cardioplegia composition has not reached yet. Propofol is used widely during the induction of anesthesia in cardiac surgery. A lot of animal studies proved a cardioprotective effect of the propofol. However, its benefits when used as a cardioplegia additives are not fully studied and it is not known whether the cardioprotective effect of propofol is different depending on the route of administration either with cardioplegia or systemically. So, this triggers us to investigate the cardioprotective effect of the propofol when added to the cardioplegia compared to systemic propofol by measuring the troponin T level. Cardiac troponin T is a good indicator of the cardioprotective effect of propofol and it was used in several studies to predict the clinical outcomes.