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Abstract Infection with H. pylori is commonly disorders such as metabolic syndrome and cardiovascular diseases, and some have been characterized by persistent and low-grade systemic inflammation. Diabetes mellitus (DM) is one of the most prevalent endocrine diseases and the importance of glycaemia control has been emphasised by studies showing that diabetic patients with higher levels of glycosylated haemoglobin (HbA1c) have more complications such as retinopathy, nephropathy and neuropathy. Infections can lead to hyperglycaemia in patients with DM because the increased production of cytokines can stimulate the secretion of insulin counter-regulatory hormones. Infection with Helicobacter pylori (H. pylori) induces gastric inflammation and has been associated with an increased production of cytokines such as tumour necrosis factor, interferon-c and interleukins. The aim of the present study was to study the possible role of eradication of Helicobacter pylori infection on glycemic control in patients with type 2 diabetes mellitus. |