الفهرس 
Pharmaceutical study on sertraline hydrochloride
CONTENTSOnly 14 pages are availabe for public view
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Abstract
Novel drug delivery dosage forms can provide improved benefits as patient compliance, reduction of adverse effects, allowing patients to receive medications as outpatients, reduction in the overall use of medicinal resources and economic benefits. Elderly people may experience deterioration in their physiological and physical abilities which may lead to encountering difficulties in taking conventional dosage forms due to hand tremors and dysphagia. Swallowing problems are also common in young people because of underdeveloped muscular and nervous system. Sublingual administration is intended where the dosage form is placed under the tongue aiming for the drug to reach directly into the blood stream through the ventral surface of the tongue and floor of the mouth. The sublingual route usually produces a faster onset of action than orally ingested drug and the portion absorbed through the sublingual vessels bypasses the hepatic first pass metabolism and thus produces acceptable bioavailability