الفهرس يوجد فقط 14 صفحة متاحة للعرض العام
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المستخلص
Background and purpose: One of the most common complaints causing exercise intolerance in patients with chronic heart failure (CHF) is inspiratory muscle weakness (IMW). Respiratory muscle dysfunction may play a role in limiting exercise capacity. Cardiac remodeling involves changes that manifest clinically as changes in size, shape, and function of the heart after injury. Long-term moderate exercise training has been shown to induce reverse remodeling in patients with stable CHF. inspiratory muscle training (IMT) improves exercise capacity and ventilatory responses to exercise in CHF patients with IMW. Aim of the study : to investigate the effect of IMT on left ventricular remodling , prognostic biomarkers (High sensitive C-reactive protein (Hs-CRP) , MIP, improving exercise tolerance indices (CPX parameters), and Quality of Life (Minnesota Living With Heart Failure Questionnaire) in chronic heart failure patients Materials and methods: : Thirty eligible male patients with chronic heart failure secondary to ischemic heart disease were selected from national heart institute heart failure outpatient clinic , their ages ranged from 50-60 years old and their ejection fraction ranged from 30-40% ,they were randomly assigned into two groups : study group which received cardiac rehabilitation ( aerobic exercise and resisted training ) plus IMT (n=15) and control group which received cardiac rehabilitation ( aerobic exercise and resisted training ) plus sham unloaded IMT (n=15), Before and after intervention, the following measures were obtained: Echcardiograph parameter (EF%, and left ventricular internal systolic dimension ) , prognostic biomarkers (Hs-CRP), maximal inspiratory muscle pressure , parameters of exercise tolerance indices ( VO2MAX , VO2%, resting heart rate , maximal heart rate , ventilatory equivalent of CO2 ) , and Quality of Life