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Abstract Surgical repair for the VSD has been the golden standard treatment. With the development of various device, trans catheter device closure of VSD has gradually become an alternative to conventional surgical repair, especially in patients with perimembranous defects with a promising success rate of closure. Objective: Assess the incidence of residual shunt following trans catheter device closure in comparison to surgical closure of pm ventricular septal defects in children. Methodology: This study is a retrospective study conducted on 200 pediatric patients post isolated pm VSD closure (100 post-surgical cases, 100 post catheter case). They were followed up over 24 months post intervention for assessment of residual shunting, possibility and timing of spontaneous closure, other early and late postoperative complications including, valves insufficiency, complete atrioventricular block (CAVB), ventricular dysfunction, blood transfusion, length of hospital stay and outcome in both groups in comparison to each other. Results: Our study revealed that 24 %(n=24) of postoperative cases had a residual defect at immediate postoperative assessment, all of them sealed spontaneously during the first 6 postoperative months, with only one post catheter case with trivial residual defect, and still present. 4%(n=4) with CAVB and permanent pacemaker among the surgical cases in opposite to none of the catheter group. As regarding the aortic insufficiency, 3% of post catheter cases developed new aortic valve regurge with trivial to mild severity (2 of them improved during the follow up), in comparison to none of the surgical cases. Blood transfusion, length of hospital stay was significantly more among the surgical cases. We have no mortality in both groups. Conclusion : Our study suggests that there is no significant difference between percutaneous and surgical closure of pmVSDs in terms of early (up to 30 days) efficacy and safety in well-selected patients. Furthermore, percutaneous closure is associated with decreased hospital stay, which could potentially be cost saving. |