الفهرس | Only 14 pages are availabe for public view |
Abstract This thesis describes the utility of isatin as a key starting material for the preparation of a novel series of isatins derivatives and studies the antimicrobial and fluorescent activities of these compounds. Synthesis of spiro[indoline-3,4'-pyridine]-3',5'-dicarbonitrile II derivatives Spiro-indoline pyridine II was synthesized to be used as a starting material for synthesizing some new heterocyclic compounds containing isatin moiety. It was found that the reaction of isatylidene malononitrile I with malononitrile and ethyl thiol in presence of ammonium acetate gave compound II when the reaction was continued for 10 min at 55 o C (Scheme A). |