Search In this Thesis
   Search In this Thesis  
العنوان
Role of Multi-Detector Computed Tomography (MDCT) in Assessment
of Biliary Neoplasms
/
المؤلف
Mohamed,Sarah Mahmoud .
هيئة الاعداد
باحث / سارة محمود محمد
مشرف / توجان طه عبد العزيز
مشرف / مينا العريان يوسف اقلاديوس
مشرف / منى حسين عبدالقادر
تاريخ النشر
2023
عدد الصفحات
190.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2023
مكان الإجازة
جامعة عين شمس - كلية الطب - Radiodiagnosis
الفهرس
Only 14 pages are availabe for public view

from 190

from 190

Abstract

Background: Biliary neoplasms are commonly encountered in the day-to-day radiological practice and can be benign or malignant. Multidetector CT (MDCT) is a noninvasive imaging modality for evaluation of patients with biliary obstruction, to localize the cause of obstruction, detect the presence of mass lesion, and define its extension and identify remote metastasis.
Objective: To find out the role of MDCT scan in the evaluation of biliary neoplasms with respect to nature, cause and level of obstruction.
Methods: During the period from January 2022 to August 2022, the present study included 30 patients with clinically suspected biliary obstruction and previously radiological or laboratory diagnosed cases of biliary malignancy after fulfilling the inclusion and exclusion criteria and taking written /verbal informed consent. 16 patients were males and 14 were females, their ages ranged between 36– 85 years with mean age of 64years old.
Results: The mean age of participants was 63.73±11.11years old; and slight male predominance (53.3%). in correlation to histopathological findings, MDCT was 95.2% sensitive in detection of cholangiocarcinoma (20/21*100). It was 100% sensitive in detection of combined cholangiocarcinoma & HCC (1/1*100). Also it was 85.75 sensitive in detection of gall bladder carcinoma (6/7*100). While it was false positive in detection a case of HCC.
The sensitivity of MDCT to detect biliary neoplasm is 96.4% (27/28*100) with specificity of 0% (0/2*100), the positive predictive value is 93.1% (27/29*100) while the negative predictive value is 0% (0/1%). We found significant association between MDCT Final outcome with resectability (P-value 0.002) and between resectability and TNM Staging (P-value <0.0001)
Conclusion: Multidetector computed tomography MDCT can be considered a noninvasive fast with high sensitivity imaging tool in the assessment of patients with biliary neoplasms. The MDCT is satisfactory for staging of biliary neoplasms and for accurate preoperative assessment of the tumor extent.